Luty 2, 2013

Systems Biology of Biochemical Signalling Research Group

Systems Biology of Biochemical Signalling

In order to survive living cells need to sense and respond to changes in their environment. Cells detect, integrate and transmit multiple extracellular signals using protein-based biochemical circuits. Multiple gene expression processes can be altered as a result. Adaptational changes then lead to new cell phenotypes that determine cells functioning. A set of biochemical reactions that deal with signal detection, transduction and decision making is often considered as cellular information processing. In our group we use a variety of theoretical and experimental approaches to provide a deeper understanding of principles that govern biochemical communication.